Splenic suppressor cells in hypogammaglobulinaemia.

Regulatory T Cells and Myeloid-Derived Suppressor Cells in Patients with Peptic Ulcer and Gastric Cancer

Background: Regulatory T Cells (Tregs) and Myeloid-Derived Suppressor Cells (MDSCs) are two main regulatory cells modulating the immune responses in inflammation and cancer. Objective: To investigate and compare Tregs and MDSCs in peptic ulcer and gastric cancer. Methods: Patients with dyspepsia were selected and divided into three groups of non-ulcer dyspepsia (NUD, n=22), peptic ulcer disease...

Splenic Immune Effector and Suppressor Cells in Mice Bearing a Growing Plasmacytoma1

The occurrence of tumor immunity in mice bearing a growing plasmacytoma (PC) was studied by local adoptive transfer assay. Spleen cells from mice with a large PC but not with a nonpalpable or small PC retarded and often inhibited entirely the growth of homologous PC. They occasionally caused late regres sion of growing homologous and heterologous PC. The individual tumor-specific immune effecto...

Splenic immune effector and suppressor cells in mice bearing a growing plasmacytoma.

The occurrence of tumor immunity in mice bearing a growing plasmacytoma (PC) was studied by local adoptive transfer assay. Spleen cells from mice with a large PC but not with a nonpalpable or small PC retarded and often inhibited entirely the growth of homologous PC. They occasionally caused late regression of growing homologous and heterologous PC. The individual tumor-specific immune effector...

Splenic Lymphoid Cells In

The capacity to respond to antigen by the production of humoral antibody arises in utero for some mammalian species but not until after birth for other species including mice (1). The development of this immunologic competence must depend in part upon the appearance and maturation of the cellular elements required for the immune response and in part upon the expression of a sufficiently wide ra...

Pathogenesis of hypogammaglobulinaemia with thymoma and late-onset hypogammaglobulinaemia.